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Phosphatidylinositol di-mannoside and derivates modulate the immune response to and efficacy of a tuberculosis protein vaccine against Mycobacterium bovis infection,
, Vaccine, Volume 30, Number 3, p.580-588, (2012)
Abstract
Chemical synthesis and immunosuppressive activity of dipalmitoyl phosphatidylinositol hexamannoside,
, Journal of Organic Chemistry, Volume 76, p.4941-4951, (2011)
Abstract
A PIM2 analogue suppresses allergic airway disease,
, Bioorganic and Medicinal Chemistry, Volume 19, p.917-925, (2011)
Abstract
Synthesis and toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues,
, Journal of Medicinal Chemistry, Volume 54, Number 20, p.7268-7279, (2011)
Abstract
Analysis of the CD1 Antigen presenting system in humanized SCID mice,
, PLoS ONE, Volume 6, (2011)
Abstract
Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells,
, Proceedings of the National Academy of Sciences of the United States of America, Volume 107, p.1535-1540, (2010)
Abstract
Regioselective approach to phosphatidylinositol 3,5-bisphosphates: Syntheses of the native phospholipid and biotinylated short-chain derivative,
, Journal of Organic Chemistry, Volume 75, p.3541-3551, (2010)
Abstract
Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function,
, Journal of Clinical Investigation, Volume 120, p.2889-2899, (2010)
Abstract
The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode,
, Journal of Experimental Medicine, Volume 207, p.2383-2393, (2010)
Abstract
2-Benzyl-myo-inositol monohydrate,
, Acta Crystallographica Section E: Structure Reports Online, Volume 65, p.o2782, (2009)
Abstract
Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2,
, PLoS ONE, Volume 4, (2009)
Abstract
The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers,
, Tetrahedron, Volume 65, p.2939-2950, (2009)
Abstract
Role of phosphatidylinositol mannosides in the interaction between mycobacteria and DC-SIGN,
, Infection and Immunity, Volume 77, p.4538-4547, (2009)
Abstract
A synthetic analogue of phosphatidylinositol mannoside is an efficient adjuvant,
, Immunopharmacology and Immunotoxicology, Volume 31, p.577-582, (2009)
Abstract
Enhanced protection against bovine tuberculosis after coadministration of Mycobacterium bovis BCG with a mycobacterial protein vaccine-adjuvant combination but not after coadministration of adjuvant alone,
, Clinical and Vaccine Immunology, Volume 15, p.765-772, (2008)
Abstract
Natural killer T-cell autoreactivity leads to a specialized activation state,
, Blood, Volume 112, p.4128-4138, (2008)
Abstract
Phosphatidylinositol mannosides are efficient mucosal adjuvants,
, Immunological Investigations, Volume 37, p.129-142, (2008)
Abstract
Phosphatidylinositol mannoside ether analogues: Syntheses and interleukin-12-inducing properties,
, Journal of Organic Chemistry, Volume 72, p.5291-5296, (2007)
Abstract
Picomolar inhibitors as transition-state probes of 5′-methylthioadenosine nucleosidases,
, ACS Chemical Biology, Volume 2, p.725-734, (2007)
Abstract
Steady-state and pre-steady-state kinetic analysis of Mycobacterium smegmatis cysteine ligase (MshC),
, Biochemistry, Volume 46, p.11421-11429, (2007)
Abstract
Synthesis and structure of phosphatidylinositol dimannoside,
, Journal of Organic Chemistry, Volume 72, p.3282-3288, (2007)
Abstract
Novel synthesis of α-galactosyl-ceramides and confirmation of their powerful NKT cell agonist activity,
, Carbohydrate Research, Volume 341, p.2785-2798, (2006)
Abstract
Phosphatidylinositol mannosides: Synthesis and adjuvant properties of phosphatidylinositol di- and tetramannosides,
, Bioorganic and Medicinal Chemistry, Volume 14, p.7615-7624, (2006)
Abstract
Phosphatidylinositol mannosides: Synthesis and suppression of allergic airway disease,
, Bioorganic and Medicinal Chemistry, Volume 14, p.5632-5642, (2006)
Abstract
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria,
, Nature Immunology, Volume 7, p.978-986, (2006)
Abstract
Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d,
, Journal of Immunology, Volume 177, p.4577-4583, (2006)
Abstract
Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae,
, Biochemistry, Volume 45, p.12929-12941, (2006)
Abstract
Femtomolar transition state analogue inhibitors of 5′- methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli,
, Journal of Biological Chemistry, Volume 280, p.18265-18273, (2005)
Abstract
Second generation transition state analogue inhibitors of human 5′-methylthioadenosine phosphorylase,
, Journal of Medicinal Chemistry, Volume 48, p.4679-4689, (2005)
Abstract
Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases,
, Journal of Biological Chemistry, Volume 280, p.30320-30328, (2005)
Abstract
Conformation inversion of an inositol derivative by use of silyl ethers: A modified route to 3,6-di-O-substituted-L-ido-tetrahydroxyazepane derivatives,
, Organic and Biomolecular Chemistry, Volume 2, p.1007-1012, (2004)
Abstract
Syntheses of tetrahydroxyazepanes from chiro-inositols and their evaluation as glycosidase inhibitors,
, Bioorganic and Medicinal Chemistry, Volume 12, p.225-232, (2004)
Abstract
Short practical synthesis of (3R,4R,5R,6A)-tetrahydroxyazepane and (3S,4S,5S,6S)-trahydroxyazepane from D- And L-chiroinositol, respectively,
, Journal of the Chemical Society, Perkin Transactions 1, p.1157-1159, (2000)
Abstract